|
KMID : 0613820170270121500
|
|
Journal of Life Science
2017 Volume.27 No. 12 p.1500 ~ p.1506
|
|
|
Lipolysis Effect of Daucosterol Isolated from Mulberry (Morus alba) Leaves
|
|
Li Ke
Lee Mi-Rim
Lu Que
Li Mei
Kang Jum-Soon
Choi Yung-Hyun
Kim Kyung-Mi
Jung Jae-Chul
Hwang Dae-Yon
Choi Young-Whan
|
|
|
Abstract
|
|
|
|
Plants are reservoirs of naturally occurring chemical compounds and of structurally diverse bioactive molecules. The aim of this investigation was to screen for the presence of phytochemicals responsible for the lipolysis activity in mulberry (Morus alba) leaves, which are important in traditional Asian medicinal plants. Powdered mulberry leaves were extracted with hexane, ethyl acetate, and methanol. Daucosterol was isolated from the EtOAc extract of mulberry leaves, and its structure was elucidated by NMR spectral analyses. The NMR assignments for the compound were determined using 1H, 13C, DEPT, COSY, HSQC, and HMBC NMR spectral data. Daucosterol showed a concentration-dependent lipolysis activity that may impart medicinal properties that can be exploited by medical practitioners for the treatment of various diseases. However, further studies should be conducted to elucidate additional mechanisms of daucosterol.
|
|
|
KEYWORD
|
|
|
Column chromatography, daucosterol, lipolysis, mulberry, NMR
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|